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Over , people in the EU have multiple sclerosis MS. It can cause blurred vision, extreme fatigue, pain, numbness, loss of movement and speech problems. It is the most common disease causing disability in young adults, and there is currently no cure. How could stem cell research help in the development of new treatments?
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Adult stem cells and multiple sclerosis
Multiple sclerosis: how could stem cells help? | Eurostemcell
Multiple sclerosis MS , a complex disorder of the central nervous system CNS , is characterized with axonal loss underlying long-term progressive disability. Currently available therapies for its management are able to slow down the progression but fail to treat it completely. Moreover, these therapies are associated with major CNS and cardiovascular adverse events, and prolonged use of these treatments may cause life-threatening diseases. Recent research has shown that cellular therapies hold a potential for CNS repair and may be able to provide protection from inflammatory damage caused after injury. Human embryonic stem cell hESC transplantation is one of the promising cell therapies; hESCs play an important role in remyelination and help in preventing demylenation of the axons.
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All rights reserved. Several clinical trials have found mesenchymal stem cell therapy effective in treating neural damage in patients with multiple sclerosis MS , according to a review published in Stem Cell Investigation. Several clinical trials have found mesenchymal stem cell MSC therapy effective in treating neural damage in patients with multiple sclerosis MS , according to a review published in Stem Cell Investigation.
Stem cells are cells in the body that can mature into specialized cells that serve a specific function. They are also able to produce exact copies of themselves. There are two main types of stem cells: embryonic stem cells and adult stem cells. Embryonic stem cells are found in the developing embryo and can mature into most types of cells in the body. The incredible flexibility of these stem cells highlights their usefulness for tissue healing and regeneration; however, there exists ethical debate over the use of stem cells from embryos.