The neurophysiology of orgasm. Upon sexual stimulation, sensory inputs from the penis are conveyed through the 1 dorsal penile nerve in men and dorsal clitoral nerve in women to the sacral segments S2—S4 of the spinal cord, where the summation of these and other sensory inputs builds up to the threshold of ejaculation or climax in women. Once this threshold is reached, intraspinal connections between the sacral and thoracolumbar segments T11—L2 , most probably through the SGE, activate the preganglionic splanchnic nerves 2 synapsing with postganglionic hypogastric nerves 3 , resulting in emission in men and in the perception of climactic threshold in women. As emission occurs in men, the semen collected in the prostatic urethra triggers a new reflex with the sacral segments of the spinal cord, leading to the contraction of the bulbospongiosus and other pelvic muscles responsible for semen expulsion.
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Science of the orgasm
Sexual Function for Men After Spinal Cord Injury - Craig Hospital
Objective: To present the current understanding of normal anatomy, physiology, sexual physiology, pathophysiology and the consequential sexual changes and dysfunctions following a spinal cord injury SCI. Methods: Narrative review of the latest literature. Results: Peripheral innervations of the pelvis involve 3 sets of efferent neurons coordinated though the pelvic plexus somatic, thoracolumbar sympathetic, and sacral parasympathetic , and these are under cerebral descending excitatory and inhibitory control. SCI, depending on the level of lesion and completeness, can alter this cerebral control, affecting the psychological and reflexogenic potential for genital arousal and also ejaculation and orgasm. During arousal, nitric oxide is the main neurotransmitter for smooth muscle relaxation in both male and female erectile tissue. In men, erection, ejaculation, and orgasm are under separate neurological control and can be individually affected by SCI.
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Sexuality after spinal cord injury
How, for example, can they explain the fact that some men and women who are paralyzed and numb below the waist are able to have orgasms? And how on Earth to explain the case of the amputee who felt his orgasms centered in that missing foot? No one -- no sexologist, no neuroscientist -- really knows.